A carefully controlled study showed substantial benefit in adults with trichotillomania; viii unfortunately, a similar study in children failed to show any similar benefit.

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While there is evidence to suggest that they could potentially be helpful in reducing OCD symptoms, they are not concretely proven to do so.

For more information on evidence-based treatment methods for OCD, please click here.

Standard treatments include exposure-based therapy and prescription medications such as the selective serotonin reuptake inhibitors (SSRIs).

These can produce significant relief for many who suffer from OCD, but not all.

When standard treatments do not produce enough improvement, or when they are unavailable or are unacceptable due to side effects or some other reason, trying less well-proven treatments may be appropriate.

A number of over-the-counter (OTC) nutritional supplements, sometimes called nutraceuticals, have been used for OCD.

In some cases there is more evidence for benefit in other disorders, such as depression, than in OCD.

Therefore, even when the evidence for benefit in OCD is fairly limited, there may be little harm in trying them in particular cases.

Sometimes they are perceived as natural, and therefore as harmless.

However, if they can affect brain chemistry in such a way as to influence OCD, mood, anxiety, or other symptoms, then they can certainly affect the brain and body in other ways, too.

They may also interact with prescribed medications that you are taking.

It is important to always discuss these supplements with your prescribing doctor, just as you would any other medication.

An additional useful source for information on some OTC supplements and herbs is the National Library of Medicine.

It is commonly used to counteract acetaminophen (Tylenol) poisoning and in the treatment of some lung ailments; the brand name typically used in hospitals is Mucomyst.

In the brain, N-AC acts both as an antioxidant and as a chemical that affects the neurotransmitter glutamate.

Because glutamate imbalance may contribute to OCD, v there has been significant interest in using N-AC as a treatment.

The evidence for its usefulness remains fairly thin, however.

In 2006, we published an early case report documenting the rapid reduction of OCD symptoms after a high dose of N-AC.

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